Text Digital Twins

James Glazier, Ph.D.

Dr. Glazier received his B.A. in Physics and Mathematics from Harvard University in 1983 and his M.S. and Ph.D. in Physics from the University of Chicago in 1987 and 1989. He has held faculty positions in Physics at the University of Notre Dame and Indiana University Bloomington and visiting positions at the University of California Santa Barbara, the University of Western Australia, the University of Grenoble in France and Tohoku University in Japan.

Dr. Glazier’s research focuses on applying physics-based computer simulations to understand embryonic development, developmental and chronic toxicity, and developmental and infectious diseases. He has worked extensively on vascular development and disfunction in Age-Related Macular Degeneration and Diabetic Retinopathy, on segmentation during early development, on Autosomal Dominant Polycystic Kidney Disease and on viral infection and immune response. He also applies these simulations to develop and optimize disease treatment.

He is an active member of numerous international research collaboration between experimental and computational biomedical scientists and is eager to develop new collaborations. He leads the collaborative development of the open-source CompuCell3D multi-scale modeling environment and participates in the development of Tissue Forge. He actively disseminates these methods, teaching an annual (now virtual) week-long workshop on multiscale virtual-tissue modeling with distribution on YouTube. He is a fellow of the American Associattion for the Advancement of Science, the American Physical Society and the Institute of Physics (London) and has served as Chair of the Division of Biological Physics of the American Physical Society. He is active in the development of infrastructure for medical digital twins and currently co-leads the IMAG/MSM Working Group on Multiscale Modeling and Viral Pandemics and the Global Alliance for Immune Prediction and Intervention (GLIMPRINT)

Video Lecture

Lecture Slides

Multi-Cellular Systems Biology: Using Virtual Tissue Computer Simulations to Explore Biological Mechanisms Across Scales for Basic Science and Medical Applications